Our project seeks to perform a randomized trial to examine the effect of 16-week supervised and unsupervised exercise interventions in sedentary, overweight, or obese Hispanic and Black cancer patients undergoing chemotherapy for the treatment of breast, colorectal, and prostate cancer. Despite the beneficial effect of exercise training for cancer patients, rates of participation in clinical cancer trials are low among disadvantaged and racial/ethnic minority groups, possibly due to greater barriers and less access to exercise training. Therefore, the need for novel accessible and cost- effective home-based exercise intervention aimed at the Hispanic and Black communities to better understand physical activity interventions is crucial.
Public health relevance
Profound disparities exist in comorbid disease risk and lifestyle behaviors during and following chemotherapy in Hispanic and Black cancer patients, compared with European American counterparts. This includes declines in cardiorespiratory fitness paired with cardiotoxic effects, placing minority cancer patients at a higher risk for cardiovascular disease.